Beta Blockers Increasing Stroke Risk


Posted on May 14, 2008

A study out of Canada is demonstrating that patients who are given blood pressure drugs known as "beta blockers" before surgery are more than one third more likely to die wtihin the month and have double the risk of stroke compared to those who recieve a placebo.  The study, which is the largest of its kind to date, is the latest in a school of thought that believes beta blockers are doing more harm than good.

Beta blockers are designed to stave off the increased blood pressure and heart rate that accompany the anticipation of surgery.  Before surgery, doctors notice an increase in the stress hormone catecholamine.  The beta blocker is supposed to block the effects that increased catecholamine has.  But the study, which used 8,000 patients at 190 hospitals across the world, indicates that they are not meeting that goal.

Dr. P.J. Devereaux, of McMaster University in Ontario authored the study.  He believes that it will stir up some debate among the medical community about whether to administer beta blockers to patients before major surgery.

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